ABO Blood Groups and How They Contribute to Blood Transfusions
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Total Duration:
Greater than 120 Minutes
Materials and Resources:
Four (6oz) plastic cups of water
Four (6oz) empty plastic cups
Food coloring-blue, green, yellow
Sharpie pen
Paper towels
Materials for students to create models (these can also be provided by the students)
Students should have had an introduction to the cardiovascular system and the components of blood.
Engage
The teacher will pose a real-life scenario to students (example below).
Scenario:
You are a doctor working in the emergency room when a patient who has been in a motorcycle accident is admitted . This patient has lost a lot of blood, and he must receive a blood transfusion. After performing a test to determine his blood type, you discover that is A+. What type of blood can he safely receive during the blood transfusion?
Note: The teacher can provide a different scenario for each group or use the same one for each group.
Allow time for students to ponder this scenario. They can provide answers through a free write individually or a think-pair-share where they discuss with a partner then share with the whole group.
Students will revisit this scenario after the activity to determine if their conclusions were correct.
Students (groups of 2 or 3) will participate in a hands-on laboratory activity in which they will “mix” blood types using colored water to see what results.
Lab Procedure:
Make a small cup of yellow water, and label it “Blood Type A”.
Make a small cup of blue water, and label it “Blood Type B”.
Make a small cup of green water, and label it “Blood Type AB”.
Pour a small amount of plain water into a cup, and label it “Blood Type O”.
Pour a small amount of one of the blood types into an empty cup (recipient). Add a second blood type to it (donor), simulating a “blood transfusion”.
Students will create a data table to display results and observations. From this information, they will determine if the transfusion was successful and which blood types are the universal donor and recipient. A color change indicates that the transfusion failed. (In a real blood transfusion, this failure would be evidenced by agglutination of the red blood cells). Note: For a more inquiry-based lesson, allow the student groups to create their own way to display results as long as they can determine which transfusions were successful.
Explain
The teacher will allow groups to share their results. The teacher will explain and discuss information related to ABO blood types and their role in blood transfusions. This information can include the following:
What is a blood type?
How do you determine a patient’s blood type?
How do you perform safe blood transfusions?
What is a universal donor and recipient?
Elaborate or Extend
Students will visit the following websites individually to practice understanding ABO blood types:
After practicing with blood-typing games, students will then revisit the opening scenario and determine if their original answers were correct and why or wrong and why. This can again be shared in a variety of ways--free write, think-pair-share, exit slips, etc.
After students feel comfortable with ABO blood types and transfusions, they will individually create a model of the four blood types demonstrating the specific presence or absence of antigens that determine each blood type. The following website or others may be used for reference.
Summarizing and explaining accurately the results of the blood transfusion lab activity.
Students completing the BrainPop quiz either online or on a hard copy.
Provided answers to the real-life scenario.
Student self-assessment will take place during practice with interactive blood typing games.
Creation of correct ABO blood type models.
Acceleration:
Extension activities could include researching and presenting on various blood disorders such as Sickle Cell Anemia, Hemophilia, Anemia, etc.
Intervention:
If students struggle with creating a way on their own to display and share lab results, teacher may provide a model data table. Printed charts summarizing the four blood types can also be used during the interactive games.
View the Special Education resources for
instructional guidance in providing modifications and adaptations
for students with significant cognitive disabilities who qualify for the Alabama Alternate Assessment.