Explore the Cell Cycle
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This learning activity provided by:
Author:
Nancy Caffee
System: Blount County School: Blount County Career Technical Center
General Activity Information
Activity ID:
2122
Title:
Explore the Cell Cycle
Digital Tool/Resource:
Cells Alive! Interactive Cell Cycle
Web Address – URL:
Overview:
This simulation uses an interactive model of the cell cycle to demonstrate the growth and maintenance of eukaryotic cells. Students can stop the cycle to observe and read about what is happening to the cell at each stage.
This activity results from the ALEX Resource Gap Project.
Associated Standards and Objectives
Content Standard(s):
Science SC2015 (2015) Grade: 9-12 Biology 4 ) Develop and use models to explain the role of the cell cycle during growth
and maintenance in multicellular organisms (e.g., normal growth and/or
uncontrolled growth resulting in tumors).
NAEP Framework
NAEP Statement:: L12.3: Cellular processes are regulated both internally and externally by environments in which cells exist, including local environments that lead to cell differentiation during the development of multicellular organisms. During the development of complex multicellular organisms, cell differentiation is regulated through the expression of different genes.
Unpacked Content
Scientific And Engineering Practices:
Developing and Using Models
Crosscutting Concepts: Systems and System Models
Disciplinary Core Idea: From Molecules to Organisms: Structures and Processes
Evidence Of Student Attainment:
Students:
Illustrate the amount of time spent in each phase of the cell cycle by a cell.
Develop and use a model to describe patterns in typical cell growth and relate those patterns to the mechanisms of cell reproduction for growth, differentiation, and repair.
Develop a model of chromosome movement and use the model to explain the maintenance of chromosome number during meiosis.
Use chromosome models to illustrate mitosis and explain the role of mitosis in maintaining populations of cells.
Use a model to demonstrate errors that may occur during cell division.
Identify the strengths and limitations of a model in representing the cell cycle and cell differentiation.
Use evidence to describe the internal and external factors that influence cell cycle control mechanisms.
Use a model to compare multiple pathways to tumor formation. Teacher Vocabulary:
Cell cycle
Chromosome
Somatic cell
Chromatin
Spindle fibers
Kinetochore microtubules
Centrioles
Centrosome
Centromere
Sister chromatids
Mitosis
Prometaphase
Prophase
Metaphase
Metaphase plate
Anaphase
Telophase
Cytokinesis
Cell plate
Cleavage furrow
Interphase
S phase
G1
G2
Growth
Maintenance
Checkpoints
Signaling factors Knowledge:
Students know:
The phases of the cell cycle (Interphase-G1, S, and G2 phases, Mitosis and cytokenisis), the amount of time spent in each cycle and what occurs during each cycle.
The process of cell cycle regulation.
Mechanisms, checkpoints and signaling factor molecules that regulate the cell cycle. Skills:
Students are able to:
Generate a graphic illustrating the amount of time a cell spends in each phase of the cell cycle.
Observe video, image or microscope slide and identify cells in each phase, relative abundance, and estimate the time spent in each phase.
Obtain and communicate information about the relationship between the cell cycle and the growth and maintenance of an organism.
Illustrate chromosome behavior during mitosis using chromosome models.
Distinguish between replicated and un-replicated chromosomes.
Demonstrate the events and cellular processes involved in each stage of mitosis.
Investigate the impact of errors in the process of cell division.
Identify the basic mechanisms, checkpoints, and general categories of signaling factor molecules (both internal and external).
Relate errors in control mechanisms to uncontrolled cell growth (cancer). Understanding:
Students understand that:
The cell cycle is necessary for growth and maintenance in multi-cellular organisms.
Mitosis only makes somatic (body) cells.
Errors in control mechanisms within the cell cycle lead to uncontrolled cell growth (cancer). AMSTI Resources:
ASIM Module: The Cell Cycle
Alabama Alternate Achievement Standards
AAS Standard: SCI.AAS.B.HS.4- Use a model to illustrate how growth occurs when cells multiply and recognize that uncontrolled growth can lead to the development of tumors (e.g., cancer).
Learning Objectives:
Students will:
use a digital model to explain the role of the cell cycle.
describe each phase of the cell cycle.
compare the time the cell spends in mitosis to interphase.
Strategies, Preparations and Variations
Phase:
During/Explore/Explain
Activity:
1. Students begin by playing the interactive simulation of the cell cycle.
2. Students click on each stage of the cell cycle beginning with interphase and ending with mitosis and observe what is happening in the cell at each point.
3. Students will complete the diagram worksheet of the cell cycle provided in the Assessment Strategy.
Assessment Strategies:
Advanced Preparation:
Students should have a brief introduction to mitosis and meiosis.
Variation Tips (optional):
Students draw their own diagram describing the cell cycle and the phases of mitosis.
Notes or Recommendations (optional):
This activity can be completed showing the whole group or individual students.
Keywords and Search Tags
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