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| Health Science (2009) |
| Grade(s): 9 - 12 |
| Introduction to Biotechnology |
| All Resources: |
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1 ) Trace the history of biotechnology.
• Identifying the scientific fields relevant to biotechnology
• Describing both scientific and non-scientific careers, roles, and responsibilities of individuals working in biotechnology
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| Health Science (2009) |
| Grade(s): 9 - 12 |
| Introduction to Biotechnology |
| All Resources: |
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2 ) Exhibit appropriate safety procedure in the laboratory.
Examples: demonstrating proper use of personal protection devices, maintaining a sanitary laboratory environment, handling biological an chemical hazards properly, following laboratory protocols, maintaining proper documentation, labeling, and record keeping
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| Health Science (2009) |
| Grade(s): 9 - 12 |
| Introduction to Biotechnology |
| All Resources: |
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3 ) Explain concepts important to solution preparation.
• Explaining the concepts of molecular mass, mole, and formula weight
• Calculating molecular mass of specific molecules and the molarity of a solution
• Preparing solutions of defined concentration
Examples: Preparing serial dilutions of specific solutions
• Adjusting the pH of specific solutions with commonly used acids and bases
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| Health Science (2009) |
| Grade(s): 9 - 12 |
| Introduction to Biotechnology |
| All Resources: |
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4 ) Correlate key cellular components to function.
Examples: nucleus, chromosome, ribosome, mitochondria
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| Health Science (2009) |
| Grade(s): 9 - 12 |
| Introduction to Biotechnology |
| All Resources: |
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5 ) Describe the process of meiosis and the cell cycle, including the hereditary significance of each.
• Comparing typical and atypical chromosome karyotypes
• Comparing spermatogenesis and oogensis using charts
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| Health Science (2009) |
| Grade(s): 9 - 12 |
| Introduction to Biotechnology |
| All Resources: |
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6 ) Describe the significance of Mendel's work to the development of the modern science of genetics, including the laws of segregation and independent assortment.
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| Health Science (2009) |
| Grade(s): 9 - 12 |
| Introduction to Biotechnology |
| All Resources: |
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7 ) Describe the inheritance patterns based on gene interactions.
• Predicting patterns of heredity using pedigree analysis
• Identifying incomplete dominance, codominance, multiple allelism
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| Health Science (2009) |
| Grade(s): 9 - 12 |
| Introduction to Biotechnology |
| All Resources: |
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8 ) Describe occurrences and effects of sex linkage, autosomal linkage, crossover, multiple alleles, and polygenes.
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| Health Science (2009) |
| Grade(s): 9 - 12 |
| Introduction to Biotechnology |
| All Resources: |
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9 ) Describe the structure and function of deoxyribonucleic acid (DNA), including replication, translation, and transcription.
• Applying the genetic code to predict amino acid sequence
• Describing methods cells use to regulate gene expression
• Defining the role of ribonucleic acid (RNA) in protein synthesis
• Performing DNA extraction and separation techniques
• Analyzing DNA previously amplified using polymerase chain reaction
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| Health Science (2009) |
| Grade(s): 9 - 12 |
| Introduction to Biotechnology |
| All Resources: |
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10 ) Explain the structure of eukaryotic chromosomes, including transposons, introns, and exons.
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| Health Science (2009) |
| Grade(s): 9 - 12 |
| Introduction to Biotechnology |
| All Resources: |
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11 ) Describe factors such as radiation, chemicals, and chance that cause mutations.
• Describing the effects of genetic variability on adaptations
• Describing how DNA mutations impact both the organism and population
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| Health Science (2009) |
| Grade(s): 9 - 12 |
| Introduction to Biotechnology |
| All Resources: |
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12 ) Explain how the Hardy-Weinberg principle provides a baseline for recognizing evolutionary changes in gene frequency due to genetic drift, gene flow, nonrandom mating, mutation, and natural selection.
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| Health Science (2009) |
| Grade(s): 9 - 12 |
| Introduction to Biotechnology |
| All Resources: |
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13 ) Differentiate among major areas in modern biotechnology, including plant, animal, microbial, forensic, and marine.
Examples: hybridization, cloning, insulin production, DNA profiling, bioremediation
• Describing techniques used with recombinant DNA
Examples: DNA sequencing, isolation of DNA segments, polymerase chain reaction
• Demonstrate proper maintenance of bacterial cultures, including preparing growth media and culturing microorganisms
• Demonstrating recombinant DNA techniques in bacteria, including performing a plasmid transformation and a restriction digest
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| Health Science (2009) |
| Grade(s): 9 - 12 |
| Introduction to Biotechnology |
| All Resources: |
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14 ) Explain the development, purpose, findings, and applications of the Human Genome Project.
• Analyzing results of the Human Genome Project to predict ethical, social, and legal implications
• Describing medical uses of gene therapy, including vaccines and tissue and antibody engineering
• Using computer bioinformatics resources to provide information regarding DNA, protein, and human genetic diseases
Examples: National Center for Biotechnology Information, protein data bank, gene reviews
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| Health Science (2009) |
| Grade(s): 9 - 12 |
| Introduction to Biotechnology |
| All Resources: |
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15 ) Describe the replication of DNA and RNA viruses, including lytic and lysogenic cycles, using diagrams.
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